Fecal microbiota transplantation (FMT) has been shown to be effective in treating patients who suffer from recurrent C. difficile infection, with a 90% cure rate. But to perform FMTs properly, donor stool must be judged safe for recipients. New information being presented during DDW highlights public stool banks as the best way to judge whether donor stool is safe for recipients.
OpenBiome, a Massachusetts-based non-profit, is the world’s first public stool bank. Dr. Zain Kassam, OpenBiome’s chief medical officer, and operations manager Laura Burns have co-authored a blog, now posted on Gastroenterology & Endoscopy News (http://www.gastroendonews.com/ViewArticle.aspx?d=Blog&d_id=558&i=May+2015&i_id=1160&a_id=32487). The blog highlights how OpenBiome is addressing a critical need for those conducting fecal microbiota transplantations (FMTs): obtaining safe fecal samples for transplant, as well as a method for processing stool under sterile conditions.
Dr. Zain and Ms. Burns are presenting abstract Sa1064, “The International Public Stool Bank: A Scalable Model for Standardized Screening and Processing of Donor Stool for Fecal Microbiota Translation,” on Saturday, May 16, in Hall C and abstract 499, “Donor Recruitment and Eligibility for Fecal Microbiota Transplantation: Results from an International Public Stool Bank,” on Monday, May 18, from 9:15-9:30 a.m., in Room 145A.